Chunyan Li
  • Research Associate Professor
  • MicroSystems and BioMEMS Lab
  • Rhodes Hall #919
  • Department of Electrical & Computer Engineering and Computer Science
  • University of Cincinnati
  • Cincinnati, Ohio 45221-0030
  • Tel: (513) 556-0852
  • Fax: (513) 556-7326
  • E-mail: Cli11@nshs.edu
  • Homepage: http://www.biomems.uc.edu/people/_chun.html
Biography
Dr. Chunyan Li completed her Ph.D. in Electrical Engineering under Dr. Ahn in 2007. She is cuurently working as a Research Scientist with North Shore Long Island Jewish Health System, New York

Research Interests

  • Micro physical and biosensors for microcatheter application
  • Packaging of micro devices.
  • Piezoelectric polymer materials (PVDF, PVDF copolymers) and devices (tactile/force sensors, IR sensor)
  • Polymer MEMS
  • BioMEMS

PATENTS APPLICATIONS AND INVENTION DISCLOSURES

  • Chong H. Ahn, Chunyan Li and Raj K. Narayan, “Flexible spirally-rolled polymer tube for monitoring and treatment of brain injuries,” US Patent Application #12/477,844, June 2009, Pending
  • Chunyan Li and Raj K. Narayan, “Micromachined flow sensor for real-time continuous regional cerebral blood flow monitoring,” November 2011, filed provisional patent application
  • Chunyan Li and etc, “Multi-channel potentiostat for reliable operation of biosensor array with different working potential and current outputs ,” 2012, in preparation for provisional patent application
  • Chunyan Li and etc, “Crosstalk-free lab-on-a-tube probe and method for making the same,” 2012, in preparation for provisional patent application
  • Chunyan Li and etc, “Method for reducing implantable biosensor biofouling by encapsulating oxygen generating biomaterial,” 2012, in preparation for provisional patent application

Publications (Journal)

  • Li C, Wu P.M, Hartings J.A, Wu Z, LeDoux D, Shutter L.A, Bailey I.B, Ramaswamy B.R, Ahn C.H and Narayan R.K. Micromachined lab-on-a-tube sensors for simultaneous brain temperature and cerebral blood flow measurements. Biomedical Microdevices 2012; 14(4): 759-768.
  • Li C, Wu P.M, Hartings J.A, Wu Z, Ahn C.H, LeDoux D, Shutter L.A and Narayan R.K. Smart catheter flow sensor for real-time continuous regional cerebral blood flow monitoring. Applied Physics Letters 2011; 99: 233705-1-233705-4. (selected for the December 15, 2011 issue of Virtual Journal of Biological Physics Research).
  • Li C, Wu P.M, Wu Z, Ahn C.H, LeDoux D, Shutter L.A, Hartings J.A and Narayan R.K. Brain temperature measurement: A study of in vitro accuracy and stability of smart catheter temperature sensors. Biomedical Microdevices 2012; 14(1): 109-118.
  • Li C, Shutter L.A, Wu P.M, Ahn C.H and Narayan R.K. Potential of a simple lab-on-a-tube for point-of care measurements of multiple analytes. Lab on a Chip 2010; 10: 1476-1479.
  • Li C, Wu P.M, Shutter L.A and Narayan R.K. Dual-mode operation of flexible piezoelectric polymer diaphragm for intracranial pressure measurement. Applied physics letters 2010; 96: 053502-1-013502-3. (selected for the February 15, 2010 issue of Virtual Journal of Biological Physics Research).
  • Li C, Wu P.M, Jung W, Ahn C.H, Shutter L.A and Narayan R.K. A novel lab-on-a-tube for multimodality neuromonitoring of patients with traumatic brain injury (TBI). Lab on a chip 2009; 9: 1988-1990. (selected for front cover).
  • Li C, Ahn C.H, Shutter L.A and Narayan R.K. Toward real-time continuous brain glucose and oxygen monitoring with a smart catheter. Biosensors and Bioelectronics 2009; 25: 173-178.
  • Li C, Wu P.M, Han J and Ahn C.H. A flexible polymer tube lab-chip integrated with microsensors for smart microcatheter. Biomedical Microdevices 2008; 10: 671-679.
  • Li C, Han J and Ahn C.H. Flexible biosensors on spirally-rolled micro tube for cardiovascular in vivo monitoring. Biosensors and Bioelectronics 2007; 22: 1988-1993.
  • Li C, Wu P.M, Lee S, Gorton A, Schulz M.M and Ahn C.H. Flexible dome and bump shape piezoelectric tactile sensors using PVDF-TrFE copolymer. IEEE/ASME Journal of Microelectromechanical Systems 2008; 17: 334-341.
  • Li C, Sauser F.E, Azizkhan R.G, Ahn C.H and Papautsky I. Polymer flip-chip bonding of pressure sensors on a flexible Kapton film for neonatal catheters. Journal Micromechanics and Microengineering 2005; 15: 1729-1735.

Publications (Conference)

Oral Proceedings

  • Li C, Wu P.M, Wu Z, Hartings J. A, Golanov E. V, Ahn C. H and Narayan R.K. Multiplexed biosensor array for continuous monitoring of cerebral oxygen tension, glucose and lactate. Biomedical Engineering Society 2012 Annual Meeting, Atlanta, Georgia, October 24-27, 2012
  • Li C, Wu Z, Hartings J. A, Rajan N, Chahine N. Cheyuo C, Wang P, Wu P. M, Golanov E. V, Ahn C. Hand Narayan R.K. Brain friendly amperometric enzyme biosensor based on encapsulated oxygengenerating biomaterial. The 34th Annual International Conference of the IEEE Engineering in Medicine & Biology Society, San Diego, CA, August 28-September 1; 2012.
  • Li C and Narayan R.K. Development of a novel catheter for early diagnosis of bacterial meningitiscaused by the ventricular drain. The 25th International Conference on Micro Electro Mechanical Systems, Paris, France, January 29-Feburary 2; 2012 (acceptance rate: 4.3%)
  • Li C, Wu P.M, Wu Z, Ahn C. H, Hartings J. A and Narayan R.K. Smart catheter flow sensor for continuous regional cerebral blood flow monitoring. Proc. Of the 11th IEEE Sensors Conference, Limerick, Ireland, October 28-31; 2011: 1417-1421
  • Li C, Hartings J.A, and Narayan R.K. Smart catheter intracortical electrodes for continuous monitoring of cerebral electrophysiology. Biomedical Engineering Society 2011 Annual Meeting, Hartford, USA, October 12-15; 2011
  • Li C and Narayan R.K. Amperometric biosensor for direct ventricular CSF lactate detection. Biomedical Engineering Society 2011 Annual Meeting, Hartford, USA, October 12-15; 2011
  • Li C, Wu P.M, Jung W, Ahn C.H, Shutter L.A and Narayan R.K. A novel lab-on-a-tube for multimodal of patients with traumatic brain injury. Proc. of the 15th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers '09), Denver, USA, June 21-25; 2009: 1449-1452. (acceptance rate: 15%)
  • Li C, Han J, Wu P.M and Ahn C.H. Temperature, Flow and Glucose Sensors Integrated With a Spirally-Rolled Polymer Tube for Cardiovascular Monitoring. Proc. of the 10th International Conference on Micro Total Analysis Systems (MicroTAS 2006), Tokyo, Japan, November 5-9; 2006: 1546-1548. (acceptance rate: 6.8%)
  • Li C, Wu P.M, Browne A, Lee S, Ahn C.H. Hot-Embossed Piezoelectric Polymer Micro-Diaphragm Arrays integrated with Lab-on-a-Chip for Protein Analysis. Proc. Of the 6th IEEE Sensors Conference, Atlanta, Georgia, USA, October 28-31; 2007: 462-465.
  • Sauser F. E, Li C, Azizkhan R.G, Ahn C.H and Papautsky I. Pressure microsensing catheters for neonatal care. Proc. Of the 3rd IEEE Sensors Conference, Vienna, Austria, October 24-27; 2004: 1475-1478.
  • Jung W, Li C, Kim D.S and Ahn C.H. A Sensing Tube with an Integrated Piezoelectric Flow Sensor for Liver Transplantation. Proc. Of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC ’09), Minneapolis, USA, Sept 2-6; 2009.

Poster Presentation

  • Narayan R.K, Li C, Ahn C. H and J. A Hartings. Development of the next generation intracranial monitor. Military Health System Research Symposium, Ft Lauderdale, Florida, August 13-16; 2012
  • Li C, Wu P.M., Hartings J.A, Wu Z, Ahn C. H and Narayan R.K. Cerebral blood flow sensor with in situ temperature and thermal conductivity compensation. 2012 The 25th International Conference on Micro Electro Mechanical Systems, Paris, France, January 29-Feburary 2; 2012
  • Li C, Jung W, Browne A, Narayan R.K and Ahn C.H A smart polymer lab-on-a-tube (LOT) with spirally-rolled microchannels for in-situ brain tumor monitoring and drug delivery. Proc. of the 12th International Conference on Miniaturized Systems for Chemistry and Life Science (MicroTAS 2008) , San Diego, USA, October 12-16, 2008; 1916-1918.
  • Li C, Sauser F.E, Azizkhan R.G, Ahn C.H and Papautsky I. Polymer flip-chip bonding of pressure sensors on flexible Kapton film for neonatal catheters. Proc. Of the 17th IEEE MEMS, Maastricht, Netherlands, January 25-29; 2004: 749-753.
  • Li C, Gao C, Han J and Ahn C.H. A new spirally-rolled polymer microtube with biosensors for smart microcatheter. Proc. of the 9th international Conference on Miniaturized System for Chemistry and Life Sciences (MicroTAS 2005), Boston, USA, September 9-13; 2005: 1203-1205.
  • Li C, Han J and Ahn C.H. Flexible biosensors integrated with a braided polymer microtube for cardiovascular in-vivo monitoring. Proc. Of the 9th World Congress on Biosensors (Biosensors 2006), Toronto, Canada, O77, May 10-12; 2006.
  • Li C, Han J and Ahn C.H. A Microcatherter Using Polymer Microtube Integrated with Physiological Biosensors. 2006 Annual Fall Meeting of the Biomedical Enginering Society, Chicago, Illinois; 2006: 683.
  • Li C, Lee S, Gorton A, Schulz M.J and Ahn C.H Dome or Bump-Shaped PVDF-TrFE Films Developed with a New Mold-Transfer Method for Flexible Tactile Sensors. Proc. of the 20th IEEE MEMS, Kobe, Japan, January 21-25; 2007: 337-340.
  • Hadlock N.A, Li C, Wolf R and Ahn C.H. A Flexible Polymer Tactile Sensor for Supporting Minimally Invasive Surgical Devices. 2006 Annual Fall Meeting of the Biomedical Enginering Society, Chicago, Illinois; 2006: 1511.
  • Lee S, Li C, Chae Y, Kang J and Ahn C.H. A fully integrated and disposable polymer biosensor using
    micro diaphragm structure of piezo-copolymer (PVDF-TrFE. Proc. of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2007), Paris, France, October 7-11; 2007: 482-484.